What is phentermine?
The Food and Drug Administration (FDA) approved it in 1959 for short-term use of up to 12 weeks for people older than 16 (1Trusted Source). Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
In the 1990s, drug makers combined phentermine with other weight loss drugs. This drug combination was commonly called fen-phen.
After reports of significant heart problems in users, the FDA pulled the other two drugs that were used in the treatment — fenfluramine and dexfenfluramine — from the market (2Trusted Source).
Today, phentermine can be used on its own and goes by the brand names Adipex-P, Lomaira, and Suprenza. You can also find it in combination medications for weight loss, such as Qsymia, which combines phentermine and another drug called topiramate.
Phentermine is a stimulant and is available if you have a prescription. Because taking phentermine comes with a risk of dependence, it is considered a controlled substance. It’s chemically similar to the stimulant amphetamine, which is also a controlled substance (3Trusted Source).
A healthcare professional may prescribe phentermine if you have obesity, defined by a body mass index (BMI) of 30 or greater. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
Healthcare professionals may also prescribe it if you have excess weight with a BMI greater than or equal to 27 and have at least one weight-related condition, such as high blood pressure, high cholesterol, or type 2 diabetes (4Trusted Source, 5Trusted Source).
However, a healthcare professional will likely recommend other weight loss strategies first, such as exercise and a calorie-reduced diet.
Phentermine belongs to a class of drugs called anorectics, also known as appetite suppressants.
Taking phentermine helps suppress your appetite, thereby limiting how many calories you eat. Over time, this can lead to weight loss.
While the exact way phentermine reduces appetite remains unclear, the drug is thought to act by increasing neurotransmitter levels in your brain (6Trusted Source, 7Trusted Source).
Neurotransmitters — the chemicals norepinephrine, serotonin, and dopamineare — are your body’s chemical messengers (6Trusted Source, 7Trusted Source).
When your levels of these three chemicals increase, your feeling of hunger decreases.
However, you may build a tolerance to the appetite-suppressing effects of phentermine within a few weeks. If that happens, speak with the healthcare professional who prescribed it. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
Phentermine is most often used for weight loss, but may also be used in combination with the medication topiramate to help with certain eating disorders, such as binge eating disorder (BED) (8Trusted Source).
Effective for weight loss. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
Several clinical studies have shown that phentermine can support meaningful weight loss.
Though the FDA approved it only for short-term use of less than 12 weeks, healthcare professionals often prescribe phentermine off-label for longer use.
Doctors may prescribe it intermittently, meaning you take a break from the medication for a set period of time before resuming it (5Trusted Source, 9Trusted Source).
The average weight loss when taking phentermine is 3% of your initial body weight after 3 months and 5–7% after 6 months. Some people report even more weight loss than this (5Trusted Source, 6Trusted Source, 9Trusted Source, 10Trusted Source).
To put this into perspective, a 5–7% weight loss is 10–14 pounds (4.5–6.4 kg) for a person who weighs 200 pounds (90.7 kg).
However, not everyone responds the same way to this medication. If you haven’t lost much weight after 3 months of using it, a healthcare professional may recommend discontinuing the medication. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
Further, its effectiveness appears to gradually decrease after prolonged use of more than a year (5Trusted Source, 6Trusted Source, 9Trusted Source, 10Trusted Source).
While phentermine has been shown to be effective for weight loss, it may work better when combined with topiramate.
Topiramate is a drug that has been used on its own to treat seizures but, like phentermine, also has appetite-reducing properties (6Trusted Source, 11Trusted Source, 12Trusted Source).
Topiramate and phentermine is a combination medication sold under the brand name Qsymia. The FDA approved it in 2012 as an addition to healthy lifestyle behaviors such as increased exercise and a calorie-reduced diet.
Compared to three other commonly prescribed drugs for weight loss, the combination of phentermine and topiramate was associated with the highest odds of losing at least 5% of initial body weight (13Trusted Source).
What’s more, a recent analysis of studies found that people who took a medication that combined phentermine and topiramate lost 16 pounds (7.3 kg) on average compared with a placebo. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
For those who took the medication for more than 56 weeks, this number increased to 17.8 pounds (8 kg) (14Trusted Source).
Furthermore, the degree of weight loss increased with the dose. Average weight loss was (14Trusted Source):
- 7.8 pounds (3.55 kg) for a 3.75/23 mg (phentermine/topiramate) dose
- 16 pounds (7.27 kg) for a 7.5/46 mg dose
- 18 pounds (8.25 kg) for a 15/92 mg dose
In users of phentermine-topiramate, weight loss translated to a significant decrease in waist circumference as well as improved insulin sensitivity, improved blood sugar management, and reduction in blood pressure (15Trusted Source, 16Trusted Source).
May be helpful for certain eating disorders
The combination of phentermine and topiramate may help reduce binge eating in people with BED and bulimia nervosa.
BED is characterized by eating large amounts of food, often quickly and to the point of discomfort. It’s also associated with a feeling of losing control during the binge, as well as feelings of shame or guilt afterward (17Trusted Source).
Bulimia nervosa involves the same binge-eating behavior as with BED but also includes behaviors people use to compensate for the effects of binge eating, such as self-induced vomiting (17Trusted Source).
In a small 12-week study in people with BED who had excess weight, people who took a phentermine and topiramate drug combination experienced significant reductions in binge-eating episode frequency (18Trusted Source). Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
In another 12-week study, people with BED or bulimia nervosa received the drug combination or a placebo (19Trusted Source).
Over 28 days, treatment with the phentermine and topiramate combination decreased the participants’ number of binge-eating days from 16.2 to 4.2. The same results were not observed in the placebo group (19Trusted Source).
While these results are promising, larger studies are still needed.
If you think you have BED, bulimia nervosa, or disordered eating, it’s important to speak with a healthcare professional.
Dosages for phentermine vary depending on its form and concentration.
Phentermine
Prior to 2016, the only available doses of phentermine were 15, 30, and 37.5 mg (7Trusted Source, 9Trusted Source).
However, since it’s a best practice for doctors to prescribe the lowest effective dose, the FDA approved an 8-mg formulation (Lomaira) in 2016, which can be taken up to three times daily at least 30 minutes before meals.
If you’re prescribed a higher dose (15, 30, or 37.5 mg), you can take it once per day in the morning before breakfast or 1–2 hours after breakfast. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
To prevent insomnia or difficulty falling or staying asleep, you should avoid taking the last dose too late in the day.
Phentermine and topiramate. Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
The combination of phentermine and topiramate — sold under the brand name Qsymia — is a medication used for weight loss.
This medication is available in four doses, ranging in strength from 3.75–15 mg of phentermine and 23–92 mg of topiramate. It’s offered in an extended-release capsule that should be taken in the morning (7Trusted Source, 9Trusted Source, 20Trusted Source). Where to buy buy adipex (phentermine topiramate) 37.5mg pink tablets online in uk without prescription, next day delivery.
After you take the lowest dose for 14 days, your doctor can choose to progress you to a higher dose (9Trusted Source, 20Trusted Source).
According to the FDA, you should stop using the medication if you don’t lose 3% of your body weight after 12 weeks on the highest daily dose (20Trusted Source).
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